Description of the operation units involved in bioproductions (for biotechnology and / or pharmaceutical applications). Enzymatic and microbial kinetics - Mass balances of catalyzers, substrate and products in bioreactors (batch, fed-batch and continuous) - Impact of the different operating conditions on process performances. Mass transport in Chromatography column and membrane processes – Description of stationary phases and membranes – Mass balance and performance calculations in tangential filtration and chromatography. Impact of the operating conditions.

2.1 Compétences à acquérir au sens « spécifiques à la matière »
Implemention and optimization of Upstream and Downstream unit operations

- Mass balance calculation
- Basic numerical integration methods
- Basic chemical reaction kinetics and thermodynamic