- Cours (CM) 12h
- Cours intégrés (CI) -
- Travaux dirigés (TD) -
- Travaux pratiques (TP) -
- Travail étudiant (TE) -
Langue de l'enseignement : Français
Description du contenu de l'enseignement
Providing basic understanding of the chemistry of d-block metals in metalloproteins and of metal-based bioactive compounds.
- Role of metal ions in biology, essential and non-essential metals.
- Methods and concepts of importance in bioinorganic chemistry.
- Cu-proteins, Cu-enzymes and their models: electron transfer, activation of oxygen and other moelcuels, oxygen transport, etc.
- Zn in bioinorganic chemistry: Zn-enzymes, structural Zn-sites and Zn as messenger.
- Transport, cell-uptake and storage of iron. Regulators of iron in a cell.
- Metals and health: metal related disease and metal-based drugs
Compétences à acquérir
- Knowing, applying and recognizing the basic principles of (bio)inorganic chemistry in/to different biological and medicinal relevant systems (metal-biomolecules, bioactive metal-complexes, etc.), including systems not treated in the teaching unit.
- Capable of understanding basic bioinorganic chemical experiments and be able to suggest potential experiments to solve a metal-related biological relevant question.
Contact
Faculté de chimie
1, rue Blaise Pascal - BP 2029667008 STRASBOURG CEDEX
0368851672
Formulaire de contact
Responsable
Peter Faller