Fondamentals of bioproduction

  • Cours (CM) 12h
  • Cours intégrés (CI) -
  • Travaux dirigés (TD) 12h
  • Travaux pratiques (TP) -
  • Travail étudiant (TE) -

Langue de l'enseignement : Anglais

Description du contenu de l'enseignement

Phénomènes de transport:
  • Mécanique des fluides, agitation, transfert de chaleur, transfert de matière.Opérations unitaires des bioprocédés :
  • Bioréacteurs, centrifugation, homogénéisation, chromatographie liquide, filtration tangentielle, extraction liquide-liquide, bilan matières, bilans thermiques. Contenus des TD :
  • Des exercices associés à chacun des chapitres du cours permettent une mise en application des concepts exposés durant ce cours

Compétences à acquérir

Students are educated in basic biotechnological process engineering subjects to perform and design upstream and basic downstream processes including :
  • Growth kinetic of microorganism and essential kinetic parameters for a improved controlling the bioprocess including sterilization kinetics of cultivation media
  • Choice and design of bioreactors and mode of operation depending on the process conditions
  • Basics in mixing, aeration and mass transport of aerobic bioprocesses
  • Basics in measurement and instrumentation of bioreactors
  • Overview of selected downstream processes
Additionally the students learn about different mechanisms of heat transfer and kinetics such as
  • heat conduction and Fourier’s law with respect to different geometries,
  • heat convection and
  • the Nußelt-similarity-theory together with dimensionless characteristics.
Furthermore they are taught how to the design and scale a continuous destillation as an example for a thermal separation process together with its balancing with respect to mass and energy and the visualisation in a McCabe-Thiele-diagram.

Contact

Responsable

Diane Takahashi